New River VDL Now Offering  LymphoPro Feline Dx

New River VDL is now offering LymphoPro Feline Dx™, patent pending. This is the most accurate test to differentiate between feline small cell lymphoma (SCL) and inflammatory bowel disease (IBD).

The test was developed in collaboration with Dr. Jörg M. Steiner (Texas A&M University) and Dr. Sina Marsilio (University of California-Davis). LymphoPro Feline Dx utilizes histology guided mass spectrometry (HGMS) profiling and machine learning algorithms for molecular differentiation of feline SCL from IBD in formalin fixed paraffin embedded (FFPE) tissues. 

Cats suffering from either condition can present with similar chronic gastrointestinal symptoms. Differentiating between these two conditions can be challenging for veterinary specialists, as histopathology often proves inconclusive, and currently available tests, such as immunohistochemistry and PCR for Antigen Receptor Rearrangements (PARR) testing, do not deliver high sensitivity and specificity. LymphoPro Feline Dx is intended to help veterinarians render a more accurate diagnosis and provide significant benefits as compared to currently available tests, such as (1) improved accuracy, (2) objective classifications, (3) faster results turnaround, and (4) less tissue required.

LymphoPro Feline Dx has been validated for feline duodenum biopsies that are either SCL or IBD. Algorithm training was performed with 39 specimens, composed of 17 SCL and 22 IBD cases. Algorithm validation was performed with an independent cohort of 54 specimens, composed of 30 SCL and 24 IBD cases, and resulted in a sensitivity of 86.7% and specificity of 91.7%. An indeterminant rate of 3.7% was observed among specimens analyzed. For the purposes of determining sensitivity and specificity, indeterminant specimens were included in the calculations.

LymphoPro Feline Dx only requires three (3), 5-micron thick serial sections of feline duodenum tissue, and test results are generally available to the ordering veterinarian within five (5) business days. The ordering veterinarian can either submit FFPE tissue sections adhered to test kit slides or one (1) FFPE tissue block.

A veterinarian, or appropriate veterinary professional, can order test kits online, and test kit orders are usually processed the same day and received by the veterinarian within three (3) business days. Tests can be ordered by filling out and submitting the relevant Test Requisition Form with the test kit. Pathology reports and any molecular test results should also be submitted with the test kit. 

Within approximately five (5) business days of test kit receipt, testing will be completed and a score will be generated that classifies the patient specimen as likely IBD, indeterminant, or SCL. The test result will then be made available to the ordering veterinarian via either email or fax.

To learn more about LymphoPro Feline Dx, veterinarians are invited to email us at or call us at (800) 850-5675.


LymphoPro Feline Dx is currently available throughout the US.

LymphoPro Feline Dx is an ancillary test intended to provide additional molecular data to aid the ordering veterinarian in the diagnostic process. This data is not intended to be used as diagnostic information without the review of the ordering veterinarian. The ordering veterinarian should consider the test result, along with all other histopathological data, clinical examinations, and other relevant findings, to make an overall diagnosis. 

LymphoPro Feline Dx was developed, and its performance characteristics determined, by New River VDL. The test has not been cleared or approved by the FDA. Patent pending.